http://tasvideos.org/userfiles/info/18706844669008296
Here's my route for the game. It skips the ending stage by retrieving the globe the 2nd time. I personally went through this game the "legit" way and the ending is exactly the same; no credits are shown. Rather than skip the dialogue, I showed it so that people can see the the end screen.
Edit:
Tricks used:
Recovering from attacks
If you were holding an item, getting hit forces you to drop it, but you'll survive. This includes normally lethal attacks such as guard dogs and the taxidermist spray.
Jumping over laser fences
There are certain laser fences (seem mostly during coop stages) that normally only Hammy could jump over. With somewhat frame precision, one can jump over as RJ. Technically not frame precise if you count getting hit, but still getting over the fence, as a success. Oh, and it seems success rate for this increases if you jump to the side of the fence.
Clipping
Get pushed out of borders by npc, scenery or objects. The last one isn't used since from testing it seems while objects can push other objects OoB, it cannot push the player out.
Quick grabbing
Running towards an object before grabbing allows you to do the "pick nothing" animation while still getting the object. The time saved is much more noticeable for heavy items or with Verne.
Skip the last level
By retrieval the blue globe again during a story mission, it confuses the game into thinking you beat the stage. While it has the unfortunate side effect of glitching the counter to say "80%", note that this is technically 100% since there's no way to reactivate last mission nor is there a way to bring the counter back up. Also beating the last level without this glitch causes the counter to say 100%
Using the mike without delay
By jumping while using the mike, you can avoid the taunt animation.