New TAS route for Enemies Vanquished:
http://www.youtube.com/watch?v=WPLjZBIQ5Q8&feature=g-upl
Saves somewhere around a minute total.
Additional improvements (will update often):
The Exchange - It's faster to go out the window to the safe after the secret meeting cutscene, as this guy does at 2:21:
http://www.youtube.com/watch?v=DDDnQkX_IXw
Night Shift - After opening the door to the Secure Terminal Room you have to wait for the terminal to come out of the floor, so during that time you can probably go decrypt Mayhew's office door then come back to the terminal fast enough to save time.
Chain Reaction - 1. Faster way through TR-2 building:
http://www.youtube.com/watch?v=31ygUAvVF0g&feature=youtu.be
2. I skipped killing one of the snipers before the long cable crossing on console 00 Agent, I heard him shooting at me but he never hit me. Hopefully that can be re-created.
3. Clip through a corner to the outside after taking the jetpack photo:
http://www.youtube.com/watch?v=Uhd3w-faEjM&feature=youtu.be
Island Infiltration - At the second gate that you open with the signal, stay back away from the gate and drive through it at full speed as it opens instead of driving directly against it.