| Id | Name | Systems | Actions |
|---|---|---|---|
| 178 | StarTropics | NES | |
| 3160 | Starwinder - The Ultimate Space Race | PSX | |
| 4089 | Steamed Hams | ZXS | |
| 1978 | Steamgear Mash | Saturn | |
| 2084 | SteamWorld Dig 2 | Linux | |
| 2575 | Steel Empire | Genesis | |
| 3868 | Steel Talons | Genesis | |
| 2663 | Steeplechase | A2600 | |
| 1184 | Stella the Cat | Genesis | |
| 4199 | Stick RPG Complete | Flash | |
| 2628 | Stick With It | Linux | |
| 2867 | Still Alive | DS | |
| 2502 | Stone Protectors | SNES | |
| 3642 | Stop the Express | ZXS | |
| 4231 | Stranded Isle | PICO8 | |
| 3729 | Strawberry Shortcake: Ice Cream Island - Riding Camp | GBA | |
| 1430 | Streemerz: Super Strength Emergency Squad Zeta | NES | |
| 3192 | Street Combat | SNES | |
| 100 | Street Fighter 2010: The Final Fight | NES | |
| 907 | Street Fighter Alpha | Arcade | |
| 960 | Street Fighter Alpha | PSX | |
| 3143 | Street Fighter Alpha 2 | PSX, SNES | |
| 873 | Street Fighter Alpha 3 | Arcade | |
| 3144 | Street Fighter Alpha 3 | PSX | |
| 2370 | Street Fighter EX Plus Alpha | PSX |