| Id | Name | Systems | Actions |
|---|---|---|---|
| 525 | Street Fighter Zero 2 Alpha | Arcade | Versions |
| 2966 | Street Fighter: The Movie | PSX | Versions |
| 3091 | Street Racing Syndicate | GBA | Versions |
| 1121 | Street Smart | Genesis | Versions |
| 115 | Streets of Rage | Genesis | Versions |
| 126 | Streets of Rage 2 | Genesis | Versions |
| 1120 | Streets of Rage 3 | Genesis | Versions |
| 136 | Strider | Genesis | Versions |
| 360 | Strider | NES | Versions |
| 3998 | Strider | Arcade | Versions |
| 508 | Strider 2 | PSX | Versions |
| 3766 | Stronghold | C64 | Versions |
| 3343 | Struggle: Antaresian Legacy | DOOM | Versions |
| 1796 | Stuart Little 2 | GBA | Versions |
| 1541 | Stuart Little: The Journey Home | GBC | Versions |
| 3090 | Stuntman | GBA | Versions |
| 3534 | Styx | ZXS | Versions |
| 420 | Sub-Terrania | Genesis | Versions |
| 2689 | Submachine 1: the Basement | Flash | Versions |
| 2281 | Suikoden II | PSX | Versions |
| 2477 | Summer Carnival '92: Recca | NES | Versions |
| 2433 | Summer Games | SMS | Versions |
| 2943 | Summon Night: Swordcraft Story | GBA | Versions |
| 274 | Sunset Riders | Genesis | Versions |
| 2597 | Sunset Riders | Arcade | Versions |