Thank you for the clarification feos. I wasn't aware that the mame debugger allowed you to change those values! I always did so via lua.
It looks like the domain I would like to access is :
"Motorola MC6800 ':maincpu' cpu space memory"
Not all values are editable in this space, but the ones that I am interested are editable.
This is not returned in the domain list within MAMEHawk. The values themselves are of course accessible via subdomains but they are chunked within ranges.
To put it simply, all of my scripts refer to a 0 offset which starts at the beginning of the main cpu space domain. If it is possible and simple to get at this fuller range of addresses that would be wonderful. I have already created a few wrapper functions for changing domains, writing / reading to the appropriate addresses etc. If this is not possible, I will just refactor, it is however a large code base and I am willing to wait if it is a simple matter!