3-tsu no E no Heya Kara no Dasshutsu 5 (3つの絵の部屋からの脱出5, Escape From the Room With the Three Portraits 5) is an escape room-style Flash game by Yomino Kagura and the fourth sequel to 3-tsu no E no Heya Kara no Dasshutsu. With more esoteric clues and puzzles along with portraits that can be interacted with, the difficulty of the series continues to ramp up.

As with their runs on the previous titles, Rxser here knows exactly what to do and finds the key to the exit as fast as possible, bypassing most of the puzzles.