| Id | Name | Systems | Actions |
|---|---|---|---|
| 4027 | SnowBall | PICO8 | |
| 3866 | Socket | Genesis | |
| 2271 | Socks the Cat Rocks the Hill | SNES | |
| 1542 | Sokoban DS | DS | |
| 227 | Solar Jetman: Hunt for the Golden Warpship | NES | |
| 3809 | Solatorobo: Red the Hunter | DS | |
| 3869 | Soldiers of Fortune | Genesis | |
| 439 | Solitaire | NES | |
| 2991 | Solomon | GBC | |
| 2325 | Solomon's Club | GB | |
| 5 | Solomon's Key | NES | |
| 13 | Solstice: The Quest for the Staff of Demnos | NES | |
| 1116 | Somari | NES | |
| 3238 | Son Son | NES | |
| 3308 | Sonic & Sega All-Stars Racing | Wii | |
| 4083 | Sonic & Sega All-Stars Racing | DS | |
| 1112 | Sonic 1: Return to the Origin | Genesis | |
| 3714 | Sonic 2.5 SAGE 2020 | PICO8 | |
| 1130 | Sonic 3 & Amy Rose | Genesis | |
| 127 | Sonic 3 & Knuckles | Genesis, Wii | |
| 3717 | Sonic 3 A.I.R. | Linux | |
| 927 | Sonic 3D Blast | Genesis | |
| 297 | Sonic Advance | GBA | |
| 256 | Sonic Advance 2 | GBA | |
| 309 | Sonic Advance 3 | GBA |