| Id | Name | Systems | Actions |
|---|---|---|---|
| 4124 | SWAT: Special Weapons and Tactics | NES | Versions |
| 1437 | Sweet Home | NES | Versions |
| 176 | Sword Master | NES | Versions |
| 2892 | Sword of Mana | GBA | Versions |
| 2269 | Sword of Vermilion | Genesis | Versions |
| 2735 | SwordQuest: EarthWorld | A2600 | Versions |
| 3270 | Swords and Serpents | NES | Versions |
| 2576 | Syd of Valis | Genesis | Versions |
| 3973 | Sylvan Tale | GG | Versions |
| 1891 | Sylvester and Tweety in Cagey Capers | Genesis | Versions |
| 843 | Syobon Action | Windows | Versions |
| 752 | Syvalion | SNES | Versions |
| 3568 | T.A.S.Q.U.A.R.E. | Linux | Versions |
| 3230 | Taboo: The Sixth Sense | NES | Versions |
| 2506 | Taekwon-Do | SNES | Versions |
| 2619 | Taiko no Tatsujin DS: Touch de Dokodon! | DS | Versions |
| 3763 | Tail Concerto | PSX | Versions |
| 2841 | Tails Adventures | GG | Versions |
| 538 | Tails in Sonic The Hedgehog | Genesis | Versions |
| 567 | Tails' Skypatrol | GG | Versions |
| 542 | Takeshi no Chousenjou | NES | Versions |
| 3159 | Tales of Destiny | PSX | Versions |
| 3193 | Tales of Phantasia | SNES | Versions |
| 2688 | Tank Racer | PSX | Versions |
| 2201 | Tapper | C64 | Versions |