Zombies Ate My Neighbours is a horror movie-themed, top-down, Run n' Gun game. Dr. Tongue has unleashed a horde of zombies and other monsters upon the world for the sole purpose of world domination. Two teens, Zeke and Julie, step forward to put an end to this madness.

This run controls both characters to save (some) survivors from zombies, vampires, crazy lumberjacks, living dolls, werewolves and other monsters. Neither character takes any damage though the 48 levels of this difficult game, using an array of weaponry from squirt guns to rocket launchers to defeat Dr. Tongue and his horde of monsters.

For a run that saves all the neighbors, see [339] SNES Zombies Ate My Neighbors "all victims saved" by Walker_Boh in 59:14.87.