3-tsu no E no Heya Kara no Dasshutsu 2 (3つの絵の部屋からの脱出2, Escape From the Room With the Three Portraits 4) is an escape room-style Flash game by Yomino Kagura and the first sequel to 3-tsu no E no Heya Kara no Dasshutsu. This iteration of the setting tries add some variety with more interesting pictures in the portraits, with one of them being a photo of the moon. Aside from that, the objective is the same where you have to find the key needed to leave the room by finding clues and solving a series of puzzles.

In this run, Rxser keeps calm, knowing exactly what to do, and finds the key and leaves the room as fast as possible.