Metal Slug X (2001) is a remixed version of Metal Slug 2, the second installment of an immensely popular run'n'gun series released on the Neo Geo MVS. The games are notable for incredibly detailed pixel graphics, fluid animation, and good humor; but the real key to their longevity is, of course, their high difficulty as far as survival goes.
You can also see more of x2poet's Metal Slug work by looking at his runs from Metal Slug, Metal Slug 3, Metal Slug 4 and Metal Slug Advance.